Getting a mortgage as a self-employed individual can be challenging due to lenders' perceptions of financial instability. To improve your chances, focus on enhancing your debt-to-income ratio by reducing debt and increasing income. Maintain substantial savings for a larger down payment and demonstrate financial stability through extensive documentation, including bank statements and tax returns. Having a well-prepared financial profile can help you secure a mortgage for a new home in Portland, designed to accommodate a home office if needed.