The safest and richest midsize Southern cities with median household incomes over $100,000 include Sugar Land, Cedar Park, Pearland, and Plano in Texas; Cary, North Carolina; Roswell, Georgia; Alexandria, Virginia; and Hoover, Alabama. These cities have populations between 75,000 and 500,000, low property and violent crime rates, high average home values, and livability scores above 80.